Livalo (Alipza)
Livalo (Alipza) contains pitavastatin, a powerful statin medication used to lower cholesterol levels and reduce cardiovascular risk. This third-generation statin offers superior cholesterol reduction with minimal drug interactions, making it an excellent choice for patients taking multiple medications or those with complex health conditions.
Pitavastatin is a member of the blood cholesterol lowering medication class of statins. Like other statins, it is an inhibitor of HMG-CoA reductase, the enzyme that catalyses the first step of cholesterol synthesis.
- Prescription Required
| Brand | Form | Price | Qty | Action |
|---|---|---|---|---|
| Alipza Generic | 4mg 30 Tablets | $48.00 | ||
| Alipza Generic | 2mg 30 Tablets | $35.00 | ||
| Alipza Generic | 1mg 30 Tablets | $24.00 |
- Please note all prices are in US dollars
Livalo (Alipza) contains pitavastatin calcium, a member of the blood cholesterol lowering medication class of statins. Like other statins in our cholesterol medications category, it is an inhibitor of HMG-CoA reductase, the enzyme that catalyses the first step of cholesterol synthesis.
People living with HIV have an increased risk of developing cardiovascular diseases. At present, little is known about preventive strategies that can prevent cardiovascular diseases in this group. The results of the phase III study REPRIEVE recently appeared in The New England Journal of Medicine and showed that Livalo (Alipza) has significant preventive effects in preventing serious cardiovascular events in people living with HIV.
When you buy Livalo online from our internet pharmacy, you’re getting a medication that has been proven effective in multiple clinical studies. This prescription drug works by competitively inhibiting HMG-CoA reductase, reducing cholesterol synthesis in the liver and promoting the uptake of circulating LDL cholesterol from the blood.
The medication is available as film-coated tablets in three strengths: 1mg, 2mg, and 4mg. Each tablet contains pitavastatin calcium equivalent to the stated amount of free base, along with inactive ingredients including lactose, hydroxypropylcellulose, hypromellose, and magnesium stearate.
For patients looking for cheap prescriptions online or seeking an alternative to expensive local pharmacies, buying Livalo through our legitimate online pharmacy provides significant cost savings. Our pharmacy online service ensures you receive genuine medication with proper storage and handling.
People living with HIV have about a 50% higher risk of a heart attack compared to people without HIV, making cholesterol management crucial for this population. The randomized, placebo-controlled phase III trial REPRIEVE has shown that treatment with Livalo can reduce the risk of serious cardiovascular events.
Similar to other cholesterol medications like Lipitor and Crestor, Livalo effectively reduces elevated LDL-C, total cholesterol, and triglycerides while increasing HDL-C levels. However, pitavastatin has unique pharmacological properties that may make it suitable for patients who experience issues with other statins.
| Brand | Alipza Generic |
|---|---|
| Form | 4mg 30 Tablets, 2mg 30 Tablets, 1mg 30 Tablets |
Like all medications, Livalo may cause side effects, though not everyone experiences them. The most commonly reported side effects in controlled clinical trials include:
Common Side Effects (affecting more than 1 in 100 people):
- Muscle pain (myalgia) - reported in 2-3% of patients
- Back pain
- Constipation
- Diarrhea
- Pain in arms or legs
Less Common Side Effects:
- Elevated blood creatinine kinase levels
- Nausea
- Headache
- Dizziness
- Abdominal pain
Serious Side Effects (rare but require immediate medical attention):
- Rhabdomyolysis (severe muscle breakdown) - extremely rare but can be life-threatening
- Liver problems - indicated by yellowing of skin or eyes, dark urine, or persistent nausea
- Severe muscle pain, tenderness, or weakness, especially with fever or unusual tiredness
- Memory problems or confusion
Muscle-Related Concerns: Muscle-related adverse events were seen in 91 participants (2.3%) in clinical studies, compared with 51 (1.4%) participants in the placebo group. Patients should report any unexplained muscle symptoms immediately to their healthcare provider.
Diabetes Risk: Clinical studies showed that diabetes mellitus was observed in 206 (5.3%) participants taking pitavastatin compared to 155 (4.0%) participants taking placebo. Regular monitoring of blood sugar levels may be recommended.
If you experience any side effects while taking Livalo, contact your healthcare provider. For patients who experience muscle-related side effects with other statins, pitavastatin may be better tolerated due to its unique metabolic pathway.
Those purchasing Livalo from international pharmacies should be aware of these potential side effects and maintain communication with their healthcare provider for proper monitoring.
Livalo (pitavastatin calcium) is indicated for:
Primary Hypercholesterolemia:
- Treatment of adults with primary hypercholesterolemia as an adjunct to diet
- Reduction of elevated total cholesterol, LDL-cholesterol, apolipoprotein B, and triglycerides
- Increase of HDL-cholesterol in patients with primary hypercholesterolemia
Mixed Dyslipidemia:
- Treatment of adults with mixed dyslipidemia when dietary modifications alone are insufficient
- Management of patients with multiple lipid abnormalities
Cardiovascular Risk Reduction:
- Prevention of cardiovascular events in high-risk patients
- Particularly beneficial for patients with HIV who have increased cardiovascular risk
- Reduction of serious cardiovascular events as demonstrated in the REPRIEVE study
Familial Hypercholesterolemia:
- Treatment of heterozygous familial hypercholesterolemia in adults
- Can be used as monotherapy or in combination with other lipid-lowering treatments
Secondary Prevention:
- Patients with established coronary heart disease
- Those with history of myocardial infarction, unstable angina, or coronary revascularization procedures
- Patients with peripheral arterial disease or history of stroke
The medication should be prescribed as part of a comprehensive treatment approach that includes:
- Appropriate dietary modifications
- Regular exercise program
- Weight management
- Smoking cessation if applicable
For patients seeking to buy meds without insurance or looking for cost plus drugs alternatives, Livalo offers an effective option for cholesterol management. The medication has been shown to be non-inferior to other statins like Atorvastatin and Simvastatin in comparative studies.
Clinical studies have demonstrated that Livalo is effective across a wide variety of patient populations regardless of race, age, or sex. The medication can be particularly useful for patients who have experienced side effects with other cholesterol medications in our heart health medications category.
Before starting Livalo, healthcare providers should rule out secondary causes of hypercholesterolemia such as poorly controlled diabetes, hypothyroidism, nephrotic syndrome, or other underlying conditions that may contribute to elevated cholesterol levels.
How much does Livalo lower cholesterol?
Clinical studies show that Livalo can reduce LDL cholesterol by 33-46% depending on the dose. The 1mg dose typically reduces LDL-C by about 33%, the 2mg dose by 38-39%, and the 4mg dose by 44-46%. Total cholesterol reduction ranges from 22-32%, while triglycerides can be reduced by 14-22%.
Can I buy Livalo online safely?
Yes, you can buy Livalo online safely through licensed internet pharmacy services. When purchasing prescription drugs online, ensure you're using a legitimate online pharmacy that requires a valid prescription. Our pharmacy provides genuine medications with proper storage and fast delivery. Always verify that any online medication source is properly licensed and regulated.
Is Livalo better than other statins for people with HIV?
Research from the REPRIEVE study specifically showed that Livalo reduced cardiovascular events in people living with HIV by 35% compared to placebo. The study found that in the pitavastatin group, serious cardiovascular events occurred at a rate of 4.81 per 1,000 person-years, compared with 7.32 in the placebo group, making it particularly effective for this population.
What's the difference between Livalo and other cholesterol medications?
Unlike other statins that are metabolized primarily through the cytochrome P450 system, Livalo is metabolized mainly through glucuronidation. This means fewer drug interactions and potentially better tolerance for patients who experienced issues with medications like Lipitor or Crestor. It's also not significantly affected by food intake.
Can Livalo cause sleep problems?
Researchers have found that fat-soluble statins like Livalo can potentially cause insomnia or nightmares in some patients. They are able to more easily cross the blood-brain barrier. If you experience sleep disturbances, discuss this with your healthcare provider, as switching to a different statin might be beneficial.
How should I take Livalo?
Take Livalo exactly as prescribed by your healthcare provider. The typical starting dose is 2mg once daily, with a maximum of 4mg daily. It can be taken with or without food and at any time of day, though taking it at the same time each day is recommended. The maximum recommended dosage is 4mg once daily - lowering the dose without consulting a healthcare provider is not advised.
What if I miss a dose of Livalo?
If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Never take a double dose to make up for a missed one. Consistency in taking the medication is important for optimal cholesterol control.
Is Livalo available as a generic?
Pitavastatin is available as both brand name Livalo and generic versions. When you buy generic drugs online USA through our pharmacy, you can find more affordable options while maintaining the same active ingredient and effectiveness. Generic pitavastatin offers the same benefits at a lower cost.
Can I stop taking Livalo once my cholesterol is normal?
If statin medication has been prescribed to lower cholesterol levels, it will probably be needed for life. Otherwise, cholesterol levels will likely go back up. Stopping the prescribed statin dosage can raise the risk of heart disease and other preventable health problems like stroke and heart attack. Always consult your healthcare provider before making any changes to your medication regimen.
Are there any drug interactions with Livalo?
Livalo should not be taken with cyclosporin or erythromycin. Discuss with a pharmacist or doctor when using Livalo in combination with other cholesterol drugs like niacin and fibrates, as these may increase risk of serious muscle problems. The medication has fewer interactions than other statins due to its unique metabolism pathway.
Where can I find cheap Livalo online?
You can find competitive prices for Livalo through legitimate online pharmacies. When looking for cheap medication online or prescription drugs cheaper than CVS, compare prices from licensed pharmacy sources. Our online pharmacy vs Amazon pricing often provides better value for prescription medications, with the added benefit of pharmacist consultation and proper medication management.
Is Livalo safe for long-term use?
Clinical studies have demonstrated Livalo's safety profile over extended periods. The medication has been studied in trials lasting up to 72 weeks, with consistent safety results. Regular monitoring through blood tests helps ensure continued safe use. Like other medications in our cholesterol category, Livalo is generally well-tolerated for long-term cholesterol management.
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The drug information provided here is only a summary and does not contain all the list of possible side effects and drug interactions regarding this medication. Be sure to contact your doctor or pharmacist if you have any specific question or concern. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a healthcare professional.
Please note that not all products, including any referenced in this page, are shipped by our affiliated Israel Pharmacy. We are affiliated with other dispensaries that ship product to our customers from the following jurisdictions: Canada, New Zealand, Turkey and United Kingdom. The items in your order maybe shipped from any of the above jurisdictions. The products are sourced from various countries as well as those listed above. Rest assured, we only affiliate with our authorized dispensaries that procure product through reliable sources.
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