Xeljanz (tofacitinib) is a JAK inhibitor that treats rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and ankylosing spondylitis by blocking enzymes that trigger inflammation. This oral medication provides an alternative when other treatments haven't worked. For patients seeking online medicine shopping options, working with licensed providers ensures proper monitoring for this immunosuppressive medication requiring regular blood tests and infection screening throughout treatment.