Crestor®/Stator® (rosuvastatin) increases healthy, high-temperature (HDL) melting levels while increasing concentrations of blocked low-temperature (LDL) structures in the body (a type of fat). Adjusting your cholesterol can help reduce heart attacks, vascular diseases, and isolate heart disease and type 2 diabetes.

Introduction

Crestor
The active ingredient in Crestor 5 / 10 / 20 / 40 MG (28 Tablets) is rosuvastatin.

Rosuvastatin belongs to the cholesterol synthesis inhibitors. They are also called statins. They inhibit the production of cholesterol in the liver and lower cholesterol and fat levels in the blood.

Doctors prescribe it for high cholesterol or a combination of high cholesterol and high fat levels in the blood. Doctors also prescribe it for people who have an increased risk of cardiovascular problems, such as those with angina or diabetes mellitus.

Side Effects

Apart from the desired effect, this drug may cause side effects.

The main side effects are as follows.

Rarely

Gastrointestinal symptoms, such as abdominal pain, constipation, flatulence, nausea, heartburn or diarrhea. These side effects occur mostly at the beginning of treatment. It usually helps if you take the medicine with some food. Do you continue to experience them after a few days? Then contact your doctor.
Headache, dizziness and a feeling of weakness. These side effects occur mainly at the beginning of treatment. Do you continue to experience them after a few days? If so, contact your doctor.
Muscle pain, joint pain, muscle weakness and muscle cramping. Usually this is harmless, but very rarely it may indicate a serious side effect on the muscles. The symptoms of this serious side effect are muscle pain, muscle weakness, feeling generally sick, fever, nausea and vomiting. The muscle pain is usually in the calves or lower back, but the whole body may also hurt. Consult with your doctor if you have unexplained muscle pain. If this muscle pain is due to the medicine, the doctor may be able to lower the dosage or prescribe another medicine. If you experience severe symptoms, consult your doctor as soon as possible.
Diabetes. You have a high risk of this if you already have elevated levels of glucose or fat in your blood, if you are overweight or if you have elevated blood pressure. Your doctor will check you for this.

Very rarely

Skin rash, itching and hives. Very rarely hair loss. These side effects disappear again when you stop taking this medicine. If this bothers you a lot, consult your doctor.
Numbness or tingling in the limbs. If you notice these side effects, contact your doctor or pharmacist.
Inflammation of the liver or pancreas and blood abnormalities. You may notice this by a sudden severe pain in the upper abdomen, tender, distended abdomen, dark urine or a yellow discoloration of the skin or whites of the eyes. If you notice these side effects, contact your doctor or pharmacist. Do you already have impaired liver function? If so, your doctor will additionally check your liver function and adjust the dosage if necessary.
Breast formation in men.
Hypersensitivity to this medicine. You may notice this by a rash, hives, swelling of the face, lips, mouth, tongue or throat, or tightness of the chest. You may also have a severe skin reaction with blisters or loosening of the skin. With all of these symptoms, you should immediately consult a doctor or go to the emergency room. You should not use this medicine in the future. Therefore, tell the pharmacy team that you are hypersensitive to rosuvastatin. They can then make sure that you do not receive this medicine and similar medicines again.
Coughing and shortness of breath. If this bothers you a lot, consult your doctor.
Edema. This is most noticeable by swollen ankles, feet and face. Consult your doctor if this affects you a lot.
Sexual disturbances, such as decreased sex drive and difficult erection. These side effects will go away when you stop taking the medicine. Contact your doctor if you experience them.
Psychological symptoms, such as anxiety, depression and memory loss. If you notice these side effects, contact your doctor or pharmacist. These side effects usually disappear again when you stop taking Rosuvastatin.
Sleep problems, such as insomnia and nightmares.

Consult your doctor if you are overly bothered by any of the above side effects or if you experience other side effects that worry you.

Pregnancy

Pregnancy
Consult with your doctor. You should NOT use this medicine if you are pregnant or plan to become pregnant soon. Not many pregnant women have used this medicine. Therefore, it is not certain if this medicine is safe for the child’s development.

Are you already using this medicine and are you pregnant or planning to become pregnant? If so, consult with your doctor. You may be able to stop taking this medicine temporarily. In most cases, stopping temporarily will not have a major impact on your health.

Breastfeeding
You should NOT use this medicine if you are breastfeeding. It is not known if it passes into breast milk or if it is harmful to the baby. You may be able to stop taking this medicine temporarily. In most cases, stopping temporarily will not have a major impact on your health. Consult with your doctor about this.

Interactions

This medicine interacts with other medicines. The text below only lists the active ingredients of these medicines, not the brand names. You can check whether your medicine contains any of these active substances in your package leaflet under the heading “composition”.

The medications with which the most important interactions occur are the following.

The anticoagulant medicines acenocoumarol and fenprocoumon. Rosuvastatin can strengthen the effect of the blood thinner. Therefore, inform the anticoagulation clinic if you start taking rosuvastatin, change the dosage, or stop taking rosuvastatin.
Gemfibrozil, another cholesterol- and fat-lowering medicine. This medicine may enhance the effects, as well as the side effects, of rosuvastatin. You may notice this in unexplained muscle pain or muscle weakness. Sometimes this combination is deliberately prescribed. Your doctor will then check your blood beforehand. Consult your doctor or pharmacist in case of unexplained severe muscle pain, muscle weakness, reduced urination or dark brown urine.
Ciclosporin, an immunosuppressant medication. In combination with rosuvastatin, this medication may increase the risk of muscle abnormalities. Consult your doctor or pharmacist in case of unexplained severe muscle pain, muscle weakness, decreased urination or dark brown urine.
The drugs against HIV and AIDS darunavir, lopinavir, ritonavir and tipranavir. In combination with rosuvastatin, these drugs increase the risk of muscle side effects. Consult with your doctor or pharmacist about this. It may be possible to reduce the dose of rosuvastatin. Consult your doctor or pharmacist in case of unexplained severe muscle pain or muscle weakness.
Colchicine, a medication for gout. This medicine makes you more likely to have side effects from rosuvastatin. Especially important here is muscle weakness. This can be recognized by rapid onset of severe and unexplained muscle pain, muscle weakness, reduced urination and brown urine. If so, stop taking rosuvastatin immediately and consult your doctor.

Are you unsure if any of the above interactions affect you? If so, contact your pharmacist or doctor.

Uses

For the correct dosage, check the pharmacy label.

When:

You may take the medicine at any time of the day. It is best to choose a fixed time, then you are less likely to forget a dose.

How long:

If this medicine brings your cholesterol levels down enough, you should probably take this medicine for life. Only if you take this medicine every day will it lower your risk of heart disease.

Forgotten

It is important to take this medicine consistently. In case you did forget a dose:

You take rosuvastatin once a day: will it be more than eight hours before you take the next tablet normally? Then take the forgotten tablet. Will it take less than eight hours? Then skip the forgotten tablet.

..to drive?
Occasionally, you may feel dizzy during the first few days of using this medicine. In this case, do not participate in traffic. After a few days, this usually passes and driving is not a problem.

..drink alcohol?
Too much alcohol is not good for the liver. Rosuvastatin can cause liver abnormalities in rare cases. Therefore, do not consume too much alcohol. One or two glasses a day is generally not a problem.

..EATING EVERYTHING?
You can eat anything. However, keeping to a cholesterol-lowering diet is essential for optimal effect of this medication. Consult with a dietician about this, if necessary.

Stopping

You can stop taking this medication at any time at once. However, your cholesterol will rise again and your risk of cardiovascular disease will also increase. Therefore, stop only in consultation with your doctor.

Rosuvastatin has been on the market internationally since 2002. It is available by prescription under the brand name Crestor in tablets.

Brand	Crestor Brand
Form	40mg 28 Tablets, 20mg 28 Tablets, 10mg 28 Tablets, 5mg 28 Tablets

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The most common side effects of rosuvastatin are headache, nausea, vomiting, diarrhea and muscle pain. The most serious side effects are liver failure, muscle breakdown (rhabdomyolysis) and kidney failure. Sever liver disease of liver failure caused by statins is very rare. More often, statins cause mild abnormalities in liver tests due to injury to the liver. The abnormalities usually disappear with continued therapy, but if the level is over three times the upper limit of normal or baseline, practitioners usually stop the statin. Liver function tests should be performed at the beginning of treatment then as needed thereafter. Rhabdomyolysis is a very rare but serious side effect of statin therapy. When used alone the frequency of rhabdomyolysis due to statins is less than one percent. Rhabdomyolysis is a process in which there is severe injury to muscles leading to severe pain and the release of muscle protein (myoglobin) into the blood. Myoglobin may cause kidney failure. To prevent the occurrence of rhabdomyolysis, patients taking statins who develop unexplained muscle pain, weakness, or tenderness should report the symptoms to their health care professional. Rosuvastatin may cause reversible increases in the amount of protein excreted by the kidneys, and in some patients kidney failure has occurred as a result. This effect depends on the dose and occurs more often at the 40 mg dose. Statins have been associated with increases in HbA1c and fasting serum glucose levels, as occur with diabetes. There are also post-marketing reports of memory loss, forgetfulness, amnesia, confusion, and memory impairment. Symptoms may start one day to years after starting treatment and resolve within a median of three weeks after stopping the statin.

Rosuvastatin is used along with a proper diet to help lower “bad” cholesterol and fats (such as LDL, triglycerides) and raise “good” cholesterol (HDL) in the blood. It belongs to a group of drugs known as “statins.” It works by reducing the amount of cholesterol made by the liver. Lowering “bad” cholesterol and triglycerides and raising “good” cholesterol decreases the risk of heart disease and helps to prevent strokes and heart attacks.In addition to eating a proper diet (such as a low cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking.

Can you ever stop taking Crestor?

Statins like Crestor inhibit the production of a substance the body needs to make cholesterol. It is known to lower low-density lipoprotein (LDL or “bad”) cholesterol and triglyceride levels, and also raise levels of high-density lipoprotein (HDL or “good”) cholesterol and apolipoproteins (apo), a principal protein constituent of HDL.

Alternate-day dosage of Crestor and other statins can be as effective as daily dosing for many individuals. It is necessary to make any change to dosing under the guidance of a doctor because to maintain the same degree of decrease in LDL, the dose of the statins taken on alternate days frequently needs to be increased.

Several clinical studies show that Crestor and other statins can reverse plaque buildup. Crestor is one of the most potent statins and can have this effect faster than others.

Measured results of lower LDL cholesterol levels can be seen as soon as two to four weeks after starting taking Crestor. These results may vary, and a doctor may adjust the dosage or frequency to reach the goals.

Crestor

Crestor is used to treat high cholesterol.

Crestor Brand	40mg 28 Tablets	$74.00	Crestor quantity
Crestor Brand	20mg 28 Tablets	$72.00	Crestor quantity
Crestor Brand	10mg 28 Tablets	$69.00	Crestor quantity
Crestor Brand	5mg 28 Tablets	$37.00	Crestor quantity

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Crestor, Rosuvastatin

Rosuvastatin

Astra Zeneca

UK, Turkey

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FAQs Crestor

Brand	Crestor Brand
Form	40mg 28 Tablets, 20mg 28 Tablets, 10mg 28 Tablets, 5mg 28 Tablets

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The drug information provided here is only a summary and does not contain all the list of possible side effects and drug interactions regarding this medication. Be sure to contact your doctor or pharmacist if you have any specific question or concern. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a healthcare professional.

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